Six Senses long ago determined wellness should be the keystone of the guests’ experience, so it created unique properties with stellar spas. At Six Senses Douro Valley, that meant a five-star eco-hotel in one of the world’s famed wine regions. Built within a 19th-century wine estate overlooking the Douro River, the resort has a wine library and a notable spa where treatments take power from the benefits of the local olives and grapes. Find bliss in one of the three Vineyard Garden Suites — located in an exclusive wing of the hotel, the 1,022-sq-ft suite has one bedroom and multiple lounge areas inside, and a generous terrace with vineyard views and a hot tub outside.